Also available in 1 mL, 5 mg, 10 mg, 25 mg, 100 mg and bulk. Please contact Fisher for quotes. Sonidegib diphosphate (LDE225 diphosphate) is a selective antagonist of Smo that inhibits murine Smo (IC501.3 nM) and human Smo (IC502.5 nM). Purity 99.86%